tlr1 protein (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

tlr1

Toll-like receptor 1. (814 aa)

Predicted Functional Partners:

tlr2

0.972

myd88

0.952

LOC101068527

0.914

tirap

0.821

tlr5

0.743

traf6

0.706

npy2r

0.699

il10

0.659

irak4

0.636

LOC101062562

0.631

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101062562	LOC101068527	ENSTRUP00000005394	ENSTRUP00000001046	Uncharacterized protein.	Toll-like receptor 18.	0.420
LOC101062562	il10	ENSTRUP00000005394	ENSTRUP00000054385	Uncharacterized protein.	Interleukin 10.	0.522
LOC101062562	irak4	ENSTRUP00000005394	ENSTRUP00000049631	Uncharacterized protein.	Interleukin-1 receptor-associated kinase 4.	0.590
LOC101062562	myd88	ENSTRUP00000005394	ENSTRUP00000050655	Uncharacterized protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.984
LOC101062562	tirap	ENSTRUP00000005394	ENSTRUP00000017584	Uncharacterized protein.	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.	0.649
LOC101062562	tlr1	ENSTRUP00000005394	ENSTRUP00000025134	Uncharacterized protein.	Toll-like receptor 1.	0.631
LOC101062562	tlr2	ENSTRUP00000005394	ENSTRUP00000007454	Uncharacterized protein.	Toll-like receptor 2.	0.420
LOC101062562	tlr5	ENSTRUP00000005394	ENSTRUP00000011331	Uncharacterized protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.902
LOC101062562	traf6	ENSTRUP00000005394	ENSTRUP00000041697	Uncharacterized protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.652
LOC101068527	LOC101062562	ENSTRUP00000001046	ENSTRUP00000005394	Toll-like receptor 18.	Uncharacterized protein.	0.420
LOC101068527	il10	ENSTRUP00000001046	ENSTRUP00000054385	Toll-like receptor 18.	Interleukin 10.	0.519
LOC101068527	myd88	ENSTRUP00000001046	ENSTRUP00000050655	Toll-like receptor 18.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.983
LOC101068527	tirap	ENSTRUP00000001046	ENSTRUP00000017584	Toll-like receptor 18.	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.	0.956
LOC101068527	tlr1	ENSTRUP00000001046	ENSTRUP00000025134	Toll-like receptor 18.	Toll-like receptor 1.	0.914
LOC101068527	tlr2	ENSTRUP00000001046	ENSTRUP00000007454	Toll-like receptor 18.	Toll-like receptor 2.	0.911
LOC101068527	tlr5	ENSTRUP00000001046	ENSTRUP00000011331	Toll-like receptor 18.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.549
LOC101068527	traf6	ENSTRUP00000001046	ENSTRUP00000041697	Toll-like receptor 18.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.414
il10	LOC101062562	ENSTRUP00000054385	ENSTRUP00000005394	Interleukin 10.	Uncharacterized protein.	0.522
il10	LOC101068527	ENSTRUP00000054385	ENSTRUP00000001046	Interleukin 10.	Toll-like receptor 18.	0.519
il10	irak4	ENSTRUP00000054385	ENSTRUP00000049631	Interleukin 10.	Interleukin-1 receptor-associated kinase 4.	0.471