klb protein (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

klb

Klotho beta. (1046 aa)

Predicted Functional Partners:

LOC101061209

0.799

fgfr1

0.725

H2S3Y8_TAKRU

0.676

CHRNA9

0.658

gcna

0.632

chrna9

0.631

flrt3

0.624

lenep

0.616

ube2k

0.613

LOC101068538

0.612

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHRNA9	gcna	ENSTRUP00000025822	ENSTRUP00000076578	Cholinergic receptor nicotinic alpha 9 subunit.	Acidic repeat-containing protein.	0.721
CHRNA9	klb	ENSTRUP00000025822	ENSTRUP00000025189	Cholinergic receptor nicotinic alpha 9 subunit.	Klotho beta.	0.658
CHRNA9	lenep	ENSTRUP00000025822	ENSTRUP00000054832	Cholinergic receptor nicotinic alpha 9 subunit.	Lens epithelial protein.	0.700
CHRNA9	ube2k	ENSTRUP00000025822	ENSTRUP00000031008	Cholinergic receptor nicotinic alpha 9 subunit.	Ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.	0.762
H2S3Y8_TAKRU	LOC101061209	ENSTRUP00000083590	ENSTRUP00000027922	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.895
H2S3Y8_TAKRU	LOC101068538	ENSTRUP00000083590	ENSTRUP00000056544	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor 4.	0.922
H2S3Y8_TAKRU	fgfr1	ENSTRUP00000083590	ENSTRUP00000042243	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.922
H2S3Y8_TAKRU	klb	ENSTRUP00000083590	ENSTRUP00000025189	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Klotho beta.	0.676
LOC101061209	H2S3Y8_TAKRU	ENSTRUP00000027922	ENSTRUP00000083590	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.895
LOC101061209	LOC101068538	ENSTRUP00000027922	ENSTRUP00000056544	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor 4.	0.950
LOC101061209	fgfr1	ENSTRUP00000027922	ENSTRUP00000042243	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.950
LOC101061209	flrt3	ENSTRUP00000027922	ENSTRUP00000046439	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Fibronectin leucine rich transmembrane 3.	0.773
LOC101061209	klb	ENSTRUP00000027922	ENSTRUP00000025189	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Klotho beta.	0.799
LOC101068538	H2S3Y8_TAKRU	ENSTRUP00000056544	ENSTRUP00000083590	Fibroblast growth factor receptor 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.922
LOC101068538	LOC101061209	ENSTRUP00000056544	ENSTRUP00000027922	Fibroblast growth factor receptor 4.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.950
LOC101068538	flrt3	ENSTRUP00000056544	ENSTRUP00000046439	Fibroblast growth factor receptor 4.	Fibronectin leucine rich transmembrane 3.	0.621
LOC101068538	klb	ENSTRUP00000056544	ENSTRUP00000025189	Fibroblast growth factor receptor 4.	Klotho beta.	0.612
chrna9	gcna	ENSTRUP00000033178	ENSTRUP00000076578	Cholinergic receptor, nicotinic, alpha 9.	Acidic repeat-containing protein.	0.706
chrna9	klb	ENSTRUP00000033178	ENSTRUP00000025189	Cholinergic receptor, nicotinic, alpha 9.	Klotho beta.	0.631
chrna9	lenep	ENSTRUP00000033178	ENSTRUP00000054832	Cholinergic receptor, nicotinic, alpha 9.	Lens epithelial protein.	0.700