Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nkx6-2NK6 homeobox 2. (279 aa)    
Predicted Functional Partners:
pdx1
Pancreatic and duodenal homeobox 1.
   
 0.563
ptf1a
Pancreas associated transcription factor 1a.
      
 0.518
nr5a2
Nuclear receptor subfamily 5, group A, member 2.
      
 0.504
LOC101076393
Nuclear receptor subfamily 5, group A, member 1a.
      
 0.504
LOC101077241
NK2 homeobox 2a.
   
  
 0.492
H2US58_TAKRU
Homeobox domain-containing protein.
   
  
 0.492
OLIG2
Class B basic helix-loop-helix protein 1/6/7.
   
  
 0.485
chga
Chromogranin A.
      
 0.476
gpatch3
G patch domain containing 3.
      
 0.475
rspry1
Ring finger and SPRY domain containing 1.
      
 0.444
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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