ece2 protein (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ece2

Endothelin converting enzyme 2b. (763 aa)

Predicted Functional Partners:

edn1

0.826

LOC101080135

0.648

ecel1

0.642

agt

0.616

LOC105417514

0.550

ednra

0.543

dhx40

0.523

ide

0.493

LOC115249042

0.461

gpalpp1

0.455

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101080135	ece2	ENSTRUP00000056210	ENSTRUP00000025288	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Endothelin converting enzyme 2b.	0.648
LOC105417514	ece2	ENSTRUP00000054766	ENSTRUP00000025288	Uncharacterized protein.	Endothelin converting enzyme 2b.	0.550
LOC105417514	ednra	ENSTRUP00000054766	ENSTRUP00000036999	Uncharacterized protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.944
LOC115249042	agt	ENSTRUP00000053814	ENSTRUP00000027299	Uncharacterized protein.	Angiotensinogen; Belongs to the serpin family.	0.409
LOC115249042	ece2	ENSTRUP00000053814	ENSTRUP00000025288	Uncharacterized protein.	Endothelin converting enzyme 2b.	0.461
LOC115249042	ecel1	ENSTRUP00000053814	ENSTRUP00000032405	Uncharacterized protein.	Endothelin converting enzyme-like 1.	0.832
LOC115249042	edn1	ENSTRUP00000053814	ENSTRUP00000052344	Uncharacterized protein.	Endothelin 1.	0.404
LOC115249042	ednra	ENSTRUP00000053814	ENSTRUP00000036999	Uncharacterized protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.972
agt	LOC115249042	ENSTRUP00000027299	ENSTRUP00000053814	Angiotensinogen; Belongs to the serpin family.	Uncharacterized protein.	0.409
agt	ece2	ENSTRUP00000027299	ENSTRUP00000025288	Angiotensinogen; Belongs to the serpin family.	Endothelin converting enzyme 2b.	0.616
agt	ecel1	ENSTRUP00000027299	ENSTRUP00000032405	Angiotensinogen; Belongs to the serpin family.	Endothelin converting enzyme-like 1.	0.600
agt	edn1	ENSTRUP00000027299	ENSTRUP00000052344	Angiotensinogen; Belongs to the serpin family.	Endothelin 1.	0.813
agt	ednra	ENSTRUP00000027299	ENSTRUP00000036999	Angiotensinogen; Belongs to the serpin family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.693
dhx40	ece2	ENSTRUP00000026109	ENSTRUP00000025288	DEAH (Asp-Glu-Ala-His) box polypeptide 40.	Endothelin converting enzyme 2b.	0.523
ece2	LOC101080135	ENSTRUP00000025288	ENSTRUP00000056210	Endothelin converting enzyme 2b.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.648
ece2	LOC105417514	ENSTRUP00000025288	ENSTRUP00000054766	Endothelin converting enzyme 2b.	Uncharacterized protein.	0.550
ece2	LOC115249042	ENSTRUP00000025288	ENSTRUP00000053814	Endothelin converting enzyme 2b.	Uncharacterized protein.	0.461
ece2	agt	ENSTRUP00000025288	ENSTRUP00000027299	Endothelin converting enzyme 2b.	Angiotensinogen; Belongs to the serpin family.	0.616
ece2	dhx40	ENSTRUP00000025288	ENSTRUP00000026109	Endothelin converting enzyme 2b.	DEAH (Asp-Glu-Ala-His) box polypeptide 40.	0.523
ece2	ecel1	ENSTRUP00000025288	ENSTRUP00000032405	Endothelin converting enzyme 2b.	Endothelin converting enzyme-like 1.	0.642