Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
irx5Iroquois homeobox 5a. (452 aa)    
Predicted Functional Partners:
irx3
Iroquois homeobox 3a.
  
  
0.689
shox
Short stature homeobox.
   
 
 0.576
sall1
Spalt-like transcription factor 1a.
      
 0.557
LOC101072563
Teashirt zinc finger homeobox 3b.
   
 0.458
hnf1a
HNF1 homeobox a.
    
 0.440
dlx1
Distal-less homeobox 1a.
   
 
 0.437
tbx4
T-box transcription factor 4.
   
  
 0.433
LOC101062006
Cdk5 and Abl enzyme substrate 2a; Belongs to the cyclin family.
      
 0.431
LOC101078824
Sphingosine-1-phosphate lyase 1.
      
 0.426
LOC101079525
Teashirt zinc finger homeobox 1.
    
 0.420
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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