Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101074952Sorting nexin 12. (243 aa)    
Predicted Functional Partners:
LOC101078809
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 0.966
LOC101078809-2
VPS35 retromer complex component.
   
 0.966
vps29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 0.961
vps26a
VPS26, retromer complex component A.
    
 0.950
snx3
Sorting nexin 3.
  
  
 
0.901
vps26b
VPS26, retromer complex component B.
    
 0.896
LOC101067116
Uncharacterized protein.
    
 0.896
LOC101076529
RAB7a, member RAS oncogene family.
   
 
 0.851
LOC101061812
RAB7A, member RAS oncogene family.
   
 
 0.851
wls
Wnt ligand secretion mediator.
    
 0.836
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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