STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ythdc1YTH domain-containing protein 1. (693 aa)    
Predicted Functional Partners:
PAPOLG
Poly(A) polymerase gamma.
   
 0.984
YTHDC2
YTH domain containing 2.
   
 0.980
Zc3h3
Zinc finger CCCH domain-containing protein 3 isoform X1.
     
 0.966
wtap
WT1 associated protein.
   
 
 0.890
mroh1
Maestro heat-like repeat family member 1.
      
 0.889
alkbh5
AlkB homolog 5, RNA demethylase.
      
 0.887
mettl14
Methyltransferase like 14; Belongs to the MT-A70-like family.
    
 
 0.881
fto
FTO alpha-ketoglutarate dependent dioxygenase.
      
 0.848
nudt21
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
   
 
 0.832
cstf1
Cleavage stimulation factor, 3' pre-RNA, subunit 1.
    
 
 0.821
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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