Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
tmem86aTransmembrane protein 86A. (243 aa)    
Predicted Functional Partners:
LOC105416426
Transmembrane protein 86B.
  
  
0.912
LOC101066332
Glycerophosphodiester phosphodiesterase domain containing 3a.
     
 0.911
gdpd1
Glycerophosphodiester phosphodiesterase domain containing 1.
     
 0.911
enpp6
Ectonucleotide pyrophosphatase/phosphodiesterase 6.
     
  0.900
lpcat4
Lysophosphatidylcholine acyltransferase 4.
     
  0.900
LOC101078122
Uncharacterized protein.
     
  0.900
enpp2
Ectonucleotide pyrophosphatase/phosphodiesterase 2.
     
  0.900
pif1
ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
      
 0.768
get3
ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]
      
 0.747
LOC101075218
Zgc:103759.
      
 0.730
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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