Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
Experiments
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[Homology]
Score
LOC101062688DEK_C domain-containing protein. (415 aa)    
Predicted Functional Partners:
baz1b
Bromodomain adjacent to zinc finger domain, 1B.
   
 0.966
LOC101064659
Uncharacterized protein.
    
 
 0.883
UPF1
Putative regulator of nonsense transcripts 1; RNA-dependent helicase and ATPase required for nonsense- mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited to mRNAs upon translation termination and undergoes a cycle of phosphorylation and dephosphorylation; its phosphorylation appears to be a key step in NMD. The formation of an rent1-rent2-rent3 surveillance complex is believed to activate NMD (By similarity).
    
 
 0.883
tbl2
MYB binding protein (P160) 1a.
    
 0.876
sf3b1
Splicing factor 3b, subunit 1.
   
 0.868
daxx
Death-domain associated protein.
    
 
 0.835
smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5.
   
 0.829
ddx21
DEAD (Asp-Glu-Ala-Asp) box helicase 21.
   
 0.809
spopl
Speckle type BTB/POZ protein like b.
    
 
 0.808
SPOP
Speckle type BTB/POZ protein.
    
 
 0.808
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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