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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lmbr1Limb development membrane protein 1; Belongs to the LIMR family. (492 aa)    
Predicted Functional Partners:
rnf32
Ring finger protein 32.
    
 
 0.746
nom1
Nucleolar protein with MIF4G domain 1.
      
 0.742
eprs1
Glutamyl-prolyl-tRNA synthetase.
    
 
 0.720
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.
      
 0.690
shh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
 
    
 0.629
LOC101073059
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
      
 0.596
ret
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
      
 0.540
lum
Lumican.
      
 0.520
zbtb16
Zinc finger and BTB domain containing 16a.
     
 0.519
chst7
Sulfotransferase; Belongs to the sulfotransferase 1 family.
     
 0.514
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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