chtf18 protein (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

chtf18

AAA domain-containing protein. (917 aa)

Predicted Functional Partners:

rfc4

0.997

rfc5

0.994

rfc2

0.993

pcna

0.991

wdhd1

0.983

pola1

0.976

rfc3

0.973

ENSTRUP00000073355

0.973

pole2

0.970

mcm2

0.961

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSTRUP00000073355	chtf18	ENSTRUP00000073355	ENSTRUP00000025955	Replication factor C (activator 1) 3.	AAA domain-containing protein.	0.973
ENSTRUP00000073355	mcm2	ENSTRUP00000073355	ENSTRUP00000018075	Replication factor C (activator 1) 3.	DNA helicase; Belongs to the MCM family.	0.859
ENSTRUP00000073355	pcna	ENSTRUP00000073355	ENSTRUP00000052987	Replication factor C (activator 1) 3.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.986
ENSTRUP00000073355	pola1	ENSTRUP00000073355	ENSTRUP00000019793	Replication factor C (activator 1) 3.	DNA polymerase.	0.822
ENSTRUP00000073355	pole2	ENSTRUP00000073355	ENSTRUP00000033726	Replication factor C (activator 1) 3.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.790
ENSTRUP00000073355	rfc2	ENSTRUP00000073355	ENSTRUP00000024932	Replication factor C (activator 1) 3.	Replication factor C (activator 1) 2.	0.992
ENSTRUP00000073355	rfc3	ENSTRUP00000073355	ENSTRUP00000066498	Replication factor C (activator 1) 3.	Replication factor C (activator 1) 3.	0.545
ENSTRUP00000073355	rfc4	ENSTRUP00000073355	ENSTRUP00000013242	Replication factor C (activator 1) 3.	Replication factor C (activator 1) 4.	0.998
ENSTRUP00000073355	rfc5	ENSTRUP00000073355	ENSTRUP00000086671	Replication factor C (activator 1) 3.	Replication factor C (activator 1) 5.	0.992
ENSTRUP00000073355	wdhd1	ENSTRUP00000073355	ENSTRUP00000039341	Replication factor C (activator 1) 3.	WD_REPEATS_REGION domain-containing protein.	0.567
chtf18	ENSTRUP00000073355	ENSTRUP00000025955	ENSTRUP00000073355	AAA domain-containing protein.	Replication factor C (activator 1) 3.	0.973
chtf18	mcm2	ENSTRUP00000025955	ENSTRUP00000018075	AAA domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.961
chtf18	pcna	ENSTRUP00000025955	ENSTRUP00000052987	AAA domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.991
chtf18	pola1	ENSTRUP00000025955	ENSTRUP00000019793	AAA domain-containing protein.	DNA polymerase.	0.976
chtf18	pole2	ENSTRUP00000025955	ENSTRUP00000033726	AAA domain-containing protein.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.970
chtf18	rfc2	ENSTRUP00000025955	ENSTRUP00000024932	AAA domain-containing protein.	Replication factor C (activator 1) 2.	0.993
chtf18	rfc3	ENSTRUP00000025955	ENSTRUP00000066498	AAA domain-containing protein.	Replication factor C (activator 1) 3.	0.973
chtf18	rfc4	ENSTRUP00000025955	ENSTRUP00000013242	AAA domain-containing protein.	Replication factor C (activator 1) 4.	0.997
chtf18	rfc5	ENSTRUP00000025955	ENSTRUP00000086671	AAA domain-containing protein.	Replication factor C (activator 1) 5.	0.994
chtf18	wdhd1	ENSTRUP00000025955	ENSTRUP00000039341	AAA domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.983