Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
scube3Signal peptide, CUB domain, EGF-like 3. (1015 aa)    
Predicted Functional Partners:
GCC2
GRIP domain-containing protein.
    
 0.736
irx3
Iroquois homeobox 3a.
    
 
 0.622
mmp9
Uncharacterized protein.
    
 0.615
LOC101065208
Usher syndrome 1C.
    
 0.610
LOC101066095
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.604
shh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.604
gpr84
G protein-coupled receptor 84.
    
 0.580
sall4
Spalt-like transcription factor 4.
      
 0.579
arid4b
Translocase of outer mitochondrial membrane 20.
    
 0.578
arid4a
AT rich interactive domain 4A (RBP1-like).
    
 0.578
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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