STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101077094Rho guanine nucleotide exchange factor (GEF) 3, like. (498 aa)    
Predicted Functional Partners:
LOC101077791
Uncharacterized protein.
    
0.583
rrad
Ras-related associated with diabetes.
    
 0.578
LOC101076770
RAS protein activator like 3.
   
  
 0.553
ap2m1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
 0.534
ap2s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
  0.534
LOC101076389
F-BAR domain-containing protein.
   
 0.528
gas7
Growth arrest-specific 7a.
   
 0.528
diras1
DIRAS family, GTP-binding RAS-like 1b.
    
 0.512
LOC101075302
Ras homolog family member F.
    
 0.497
LOC101076147
Uncharacterized protein.
    
 0.497
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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