LOC101077094 protein (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

LOC101077094

Rho guanine nucleotide exchange factor (GEF) 3, like. (498 aa)

Predicted Functional Partners:

mier3

0.630

ap2m1

0.584

diras1

0.574

rrad

0.570

ap2s1

0.550

LOC101064039

0.546

LOC101076770

0.523

gem

0.500

tmem104

0.497

papss2

0.487

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101064039	LOC101077094	ENSTRUP00000079969	ENSTRUP00000026382	A kinase (PRKA) anchor protein 12b.	Rho guanine nucleotide exchange factor (GEF) 3, like.	0.546
LOC101064039	rrad	ENSTRUP00000079969	ENSTRUP00000044175	A kinase (PRKA) anchor protein 12b.	Ras-related associated with diabetes.	0.469
LOC101076770	LOC101077094	ENSTRUP00000008361	ENSTRUP00000026382	RAS protein activator like 3.	Rho guanine nucleotide exchange factor (GEF) 3, like.	0.523
LOC101076770	rrad	ENSTRUP00000008361	ENSTRUP00000044175	RAS protein activator like 3.	Ras-related associated with diabetes.	0.570
LOC101077094	LOC101064039	ENSTRUP00000026382	ENSTRUP00000079969	Rho guanine nucleotide exchange factor (GEF) 3, like.	A kinase (PRKA) anchor protein 12b.	0.546
LOC101077094	LOC101076770	ENSTRUP00000026382	ENSTRUP00000008361	Rho guanine nucleotide exchange factor (GEF) 3, like.	RAS protein activator like 3.	0.523
LOC101077094	ap2m1	ENSTRUP00000026382	ENSTRUP00000068352	Rho guanine nucleotide exchange factor (GEF) 3, like.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.584
LOC101077094	ap2s1	ENSTRUP00000026382	ENSTRUP00000072937	Rho guanine nucleotide exchange factor (GEF) 3, like.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.550
LOC101077094	diras1	ENSTRUP00000026382	ENSTRUP00000072707	Rho guanine nucleotide exchange factor (GEF) 3, like.	DIRAS family, GTP-binding RAS-like 1b.	0.574
LOC101077094	gem	ENSTRUP00000026382	ENSTRUP00000025706	Rho guanine nucleotide exchange factor (GEF) 3, like.	GTP binding protein overexpressed in skeletal muscle.	0.500
LOC101077094	mier3	ENSTRUP00000026382	ENSTRUP00000052592	Rho guanine nucleotide exchange factor (GEF) 3, like.	Mesoderm induction early response 1, family member 3 b.	0.630
LOC101077094	papss2	ENSTRUP00000026382	ENSTRUP00000025210	Rho guanine nucleotide exchange factor (GEF) 3, like.	3'-phosphoadenosine 5'-phosphosulfate synthase 2a.	0.487
LOC101077094	rrad	ENSTRUP00000026382	ENSTRUP00000044175	Rho guanine nucleotide exchange factor (GEF) 3, like.	Ras-related associated with diabetes.	0.570
LOC101077094	tmem104	ENSTRUP00000026382	ENSTRUP00000050043	Rho guanine nucleotide exchange factor (GEF) 3, like.	Transmembrane protein 104.	0.497
ap2m1	LOC101077094	ENSTRUP00000068352	ENSTRUP00000026382	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Rho guanine nucleotide exchange factor (GEF) 3, like.	0.584
ap2m1	ap2s1	ENSTRUP00000068352	ENSTRUP00000072937	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.999
ap2s1	LOC101077094	ENSTRUP00000072937	ENSTRUP00000026382	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Rho guanine nucleotide exchange factor (GEF) 3, like.	0.550
ap2s1	ap2m1	ENSTRUP00000072937	ENSTRUP00000068352	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.999
diras1	LOC101077094	ENSTRUP00000072707	ENSTRUP00000026382	DIRAS family, GTP-binding RAS-like 1b.	Rho guanine nucleotide exchange factor (GEF) 3, like.	0.574
gem	LOC101077094	ENSTRUP00000025706	ENSTRUP00000026382	GTP binding protein overexpressed in skeletal muscle.	Rho guanine nucleotide exchange factor (GEF) 3, like.	0.500