Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SMTNSmoothelin. (942 aa)    
Predicted Functional Partners:
LOC101073992
Uncharacterized protein.
      
 0.746
fam171a1
Family with sequence similarity 171 member A1.
      
 0.697
fam171a2
Uncharacterized protein.
      
 0.697
LOC101073550
Zgc:153115.
      
 0.632
LOC101061306
Cysteine-serine-rich nuclear protein 1a.
      
 0.621
LOC101064414
Cysteine-serine-rich nuclear protein 1b.
      
 0.621
LOC101070157
KH and NYN domain containing.
   
  
 0.605
ADGRA1
Adhesion G protein-coupled receptor A1; Belongs to the G-protein coupled receptor 2 family.
      
 0.593
adgra2
Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family.
      
 0.593
LOC101073139
Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
   
  
 0.584
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (18%) [HD]