Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
zbtb33Zinc finger and BTB domain containing 33. (624 aa)    
Predicted Functional Partners:
CTNND1
Catenin delta 1.
    
 
 0.857
LOC101067270
Catenin (cadherin-associated protein), delta 1.
    
 
 0.857
ARVCF
ARVCF delta catenin family member b.
    
 
 0.857
LOC101077861
Catenin (cadherin-associated protein), delta 2a.
    
 
 0.749
ctnnd2
Catenin (cadherin-associated protein), delta 2b.
    
 
 0.749
PKP4
Plakophilin 4.
    
 
 0.749
ncor2
Nuclear receptor corepressor 2.
    
 0.715
ncor1
Nuclear receptor corepressor 1.
    
 0.715
nkrf
NFKB repressing factor.
      
 0.701
LOC101079595
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.688
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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