Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
rmi1RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (536 aa)    
Predicted Functional Partners:
rmi2
RecQ mediated genome instability 2.
    
 0.999
blm
BLM RecQ like helicase.
   
 0.996
top3a-2
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.992
top3a
DNA topoisomerase 3-alpha.
    
 0.992
Fancm
ERCC4 domain-containing protein.
   
 0.987
rpa3
Replication protein A3.
    
 0.979
ercc6l
Excision repair cross-complementation group 6-like.
    
 
 0.976
fancf
FA complementation group F.
    
 
 0.970
mus81
MUS81 structure-specific endonuclease subunit.
   
 0.962
FANCA
Fanconi anemia group A protein.
    
 
 0.962
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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