Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
foxe1Forkhead box E1. (365 aa)    
Predicted Functional Partners:
H2UXB1_TAKRU
COesterase domain-containing protein.
    
 0.649
plk3
Serine/threonine-protein kinase PLK.
   
 0.581
itpk1
Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Belongs to the ITPK1 family.
    
 
 0.564
msx1
Homeobox domain-containing protein.
    
 
 0.553
hhex
Homeobox domain-containing protein.
      
 0.517
gpr161
G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family.
      
 0.513
perp
P53 apoptosis effector related to pmp22.
   
  
 0.480
nkx2-1
NK2 homeobox 1.
   
 0.479
nkx2-4
NK2 homeobox 4.
   
 0.479
mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast).
   
   0.467
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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