Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
trmotRNA methyltransferase O. (466 aa)    
Predicted Functional Partners:
hsbp1
Heat shock factor binding protein 1a.
    
   0.789
tango2
Transport and golgi organization 2 homolog (Drosophila).
      
 0.708
timm21
Translocase of inner mitochondrial membrane 21.
      
 0.701
LOC101064065
VPS37C subunit of ESCRT-I.
      
 0.698
ube2w
UBIQUITIN_CONJUGAT_2 domain-containing protein.
      
 0.698
tomm22
Translocase of outer mitochondrial membrane 22 homolog (yeast).
      
 0.578
LOC101070151
Poly [ADP-ribose] polymerase.
    
   0.564
LOC101061340
Poly [ADP-ribose] polymerase.
    
   0.564
LOC101075019
tRNA-yW synthesizing protein 1 homolog (S. cerevisiae).
  
  
 0.559
LOC101073942
Cytochrome c oxidase assembly factor COX18.
      
 0.546
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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