six4 protein (Takifugu rubripes) - STRING interaction network

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

six4

SIX homeobox 4a. (682 aa)

Predicted Functional Partners:

eya3

0.605

LOC101079015

0.605

eya4

0.605

eya1

0.605

RAB19

0.471

LOC101063247

0.454

RAB8A

0.454

LOC101071476

0.440

setd2

0.422

hoxc13

0.415

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101063247	RAB8A	ENSTRUP00000049701	ENSTRUP00000081510	RAB8A, member RAS oncogene family.	RAB8A, member RAS oncogene family.	0.900
LOC101063247	hoxc13	ENSTRUP00000049701	ENSTRUP00000065813	RAB8A, member RAS oncogene family.	Homeobox protein Hox-C13a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family.	0.420
LOC101063247	six4	ENSTRUP00000049701	ENSTRUP00000027004	RAB8A, member RAS oncogene family.	SIX homeobox 4a.	0.454
LOC101071476	hoxc13	ENSTRUP00000071723	ENSTRUP00000065813	RAB27B, member RAS oncogene family.	Homeobox protein Hox-C13a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family.	0.491
LOC101071476	six4	ENSTRUP00000071723	ENSTRUP00000027004	RAB27B, member RAS oncogene family.	SIX homeobox 4a.	0.440
LOC101079015	eya3	ENSTRUP00000034935	ENSTRUP00000029556	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.470
LOC101079015	six4	ENSTRUP00000034935	ENSTRUP00000027004	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	SIX homeobox 4a.	0.605
RAB19	six4	ENSTRUP00000067087	ENSTRUP00000027004	RAB19, member RAS oncogene family.	SIX homeobox 4a.	0.471
RAB8A	LOC101063247	ENSTRUP00000081510	ENSTRUP00000049701	RAB8A, member RAS oncogene family.	RAB8A, member RAS oncogene family.	0.900
RAB8A	hoxc13	ENSTRUP00000081510	ENSTRUP00000065813	RAB8A, member RAS oncogene family.	Homeobox protein Hox-C13a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family.	0.420
RAB8A	six4	ENSTRUP00000081510	ENSTRUP00000027004	RAB8A, member RAS oncogene family.	SIX homeobox 4a.	0.454
eya1	eya3	ENSTRUP00000087800	ENSTRUP00000029556	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.473
eya1	six4	ENSTRUP00000087800	ENSTRUP00000027004	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	SIX homeobox 4a.	0.605
eya3	LOC101079015	ENSTRUP00000029556	ENSTRUP00000034935	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.470
eya3	eya1	ENSTRUP00000029556	ENSTRUP00000087800	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.473
eya3	eya4	ENSTRUP00000029556	ENSTRUP00000087636	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog 4; Tyrosine phosphatase that specifically dephosphorylates 'Tyr- 142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye (By similarity); B [...]	0.472
eya3	six4	ENSTRUP00000029556	ENSTRUP00000027004	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	SIX homeobox 4a.	0.605
eya4	eya3	ENSTRUP00000087636	ENSTRUP00000029556	Eyes absent homolog 4; Tyrosine phosphatase that specifically dephosphorylates 'Tyr- 142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye (By similarity); B [...]	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.472
eya4	six4	ENSTRUP00000087636	ENSTRUP00000027004	Eyes absent homolog 4; Tyrosine phosphatase that specifically dephosphorylates 'Tyr- 142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye (By similarity); B [...]	SIX homeobox 4a.	0.605
hoxc13	LOC101063247	ENSTRUP00000065813	ENSTRUP00000049701	Homeobox protein Hox-C13a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family.	RAB8A, member RAS oncogene family.	0.420