fbxo42 protein (Takifugu rubripes) - STRING interaction network

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Score

fbxo42

F-box protein 42. (694 aa)

Predicted Functional Partners:

skp1

0.919

rbpj

0.890

ccdc6

0.870

LOC101079595

0.850

LOC115248454

0.841

LOC101079814

0.841

cul3

0.837

fbxo41

0.820

chek2

0.749

sirt6

0.683

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101079595	LOC101079814	ENSTRUP00000030644	ENSTRUP00000070060	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Ring-box 1, E3 ubiquitin protein ligase.	0.703
LOC101079595	LOC115248454	ENSTRUP00000030644	ENSTRUP00000061990	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	RING-box protein 1.	0.703
LOC101079595	chek2	ENSTRUP00000030644	ENSTRUP00000035807	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Checkpoint kinase 2.	0.999
LOC101079595	fbxo42	ENSTRUP00000030644	ENSTRUP00000027213	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	F-box protein 42.	0.850
LOC101079595	sirt6	ENSTRUP00000030644	ENSTRUP00000078257	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Sirtuin 6.	0.500
LOC101079595	skp1	ENSTRUP00000030644	ENSTRUP00000019939	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.524
LOC101079814	LOC101079595	ENSTRUP00000070060	ENSTRUP00000030644	Ring-box 1, E3 ubiquitin protein ligase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.703
LOC101079814	LOC115248454	ENSTRUP00000070060	ENSTRUP00000061990	Ring-box 1, E3 ubiquitin protein ligase.	RING-box protein 1.	0.900
LOC101079814	cul3	ENSTRUP00000070060	ENSTRUP00000024763	Ring-box 1, E3 ubiquitin protein ligase.	Cullin 3a; Belongs to the cullin family.	0.992
LOC101079814	fbxo41	ENSTRUP00000070060	ENSTRUP00000061123	Ring-box 1, E3 ubiquitin protein ligase.	F-box protein 41.	0.611
LOC101079814	fbxo42	ENSTRUP00000070060	ENSTRUP00000027213	Ring-box 1, E3 ubiquitin protein ligase.	F-box protein 42.	0.841
LOC101079814	skp1	ENSTRUP00000070060	ENSTRUP00000019939	Ring-box 1, E3 ubiquitin protein ligase.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.998
LOC115248454	LOC101079595	ENSTRUP00000061990	ENSTRUP00000030644	RING-box protein 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.703
LOC115248454	LOC101079814	ENSTRUP00000061990	ENSTRUP00000070060	RING-box protein 1.	Ring-box 1, E3 ubiquitin protein ligase.	0.900
LOC115248454	cul3	ENSTRUP00000061990	ENSTRUP00000024763	RING-box protein 1.	Cullin 3a; Belongs to the cullin family.	0.992
LOC115248454	fbxo41	ENSTRUP00000061990	ENSTRUP00000061123	RING-box protein 1.	F-box protein 41.	0.611
LOC115248454	fbxo42	ENSTRUP00000061990	ENSTRUP00000027213	RING-box protein 1.	F-box protein 42.	0.841
LOC115248454	skp1	ENSTRUP00000061990	ENSTRUP00000019939	RING-box protein 1.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.998
ccdc6	fbxo42	ENSTRUP00000055231	ENSTRUP00000027213	Coiled-coil domain containing 6a.	F-box protein 42.	0.870
chek2	LOC101079595	ENSTRUP00000035807	ENSTRUP00000030644	Checkpoint kinase 2.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.999