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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbxo42F-box protein 42. (694 aa)    
Predicted Functional Partners:
cul3
Cullin 3a; Belongs to the cullin family.
    
 
 0.634
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 
 0.578
chek2
Checkpoint kinase 2.
   
 
 0.574
sirt6
Sirtuin 6.
      
 0.566
pole2
DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.
    
 
 0.494
drg1
Developmentally regulated GTP binding protein 1.
    
   0.483
cs
Citrate synthase; Belongs to the citrate synthase family.
    
   0.483
ENSTRUP00000047990
Uncharacterized protein.
    
   0.483
c9hxorf56
UPF0428 protein CXorf56 homolog.
    
   0.483
ptpn21
Protein tyrosine phosphatase non-receptor type 21.
      
 0.457
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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