Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nkx2-5NK2 homeobox 5. (324 aa)    
Predicted Functional Partners:
gata4
GATA binding protein 4.
   
 0.986
tbx4
T-box transcription factor 4.
   
 0.972
tbx20
T-box transcription factor 20.
   
 0.963
gata6
GATA binding protein 6.
   
 0.949
mef2b
Myocyte enhancer factor 2b.
    
 0.945
gata5
Transcription factor GATA-5 isoform X1.
   
 0.930
mef2c
Myocyte enhancer factor 2cb.
    
 0.887
LOC101076507
MADS-box domain-containing protein.
    
 0.852
mef2a
Myocyte enhancer factor 2aa.
    
 0.852
LOC101069919
GATA binding protein 1a.
   
 0.816
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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