| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Fech | coq2 | ENSTRUP00000065422 | ENSTRUP00000043156 | Protoporphyrin/coproporphyrin ferrochelatase. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.714 |
| Fech | coq3 | ENSTRUP00000065422 | ENSTRUP00000000572 | Protoporphyrin/coproporphyrin ferrochelatase. | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 0.667 |
| Fech | hmbs | ENSTRUP00000065422 | ENSTRUP00000085986 | Protoporphyrin/coproporphyrin ferrochelatase. | Hydroxymethylbilane synthase a. | 0.793 |
| Fech | itih2 | ENSTRUP00000065422 | ENSTRUP00000027282 | Protoporphyrin/coproporphyrin ferrochelatase. | Inter-alpha-trypsin inhibitor heavy chain 2. | 0.550 |
| Fech | ppox | ENSTRUP00000065422 | ENSTRUP00000011985 | Protoporphyrin/coproporphyrin ferrochelatase. | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.999 |
| H2UMT2_TAKRU | gmps | ENSTRUP00000079437 | ENSTRUP00000066154 | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | Guanine monophosphate synthase. | 0.920 |
| H2UMT2_TAKRU | itih2 | ENSTRUP00000079437 | ENSTRUP00000027282 | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | Inter-alpha-trypsin inhibitor heavy chain 2. | 0.647 |
| NT5E | gmps | ENSTRUP00000011279 | ENSTRUP00000066154 | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | Guanine monophosphate synthase. | 0.920 |
| NT5E | itih2 | ENSTRUP00000011279 | ENSTRUP00000027282 | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | Inter-alpha-trypsin inhibitor heavy chain 2. | 0.647 |
| coq2 | Fech | ENSTRUP00000043156 | ENSTRUP00000065422 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Protoporphyrin/coproporphyrin ferrochelatase. | 0.714 |
| coq2 | coq3 | ENSTRUP00000043156 | ENSTRUP00000000572 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 0.809 |
| coq2 | hmbs | ENSTRUP00000043156 | ENSTRUP00000085986 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Hydroxymethylbilane synthase a. | 0.708 |
| coq2 | itih2 | ENSTRUP00000043156 | ENSTRUP00000027282 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Inter-alpha-trypsin inhibitor heavy chain 2. | 0.614 |
| coq3 | Fech | ENSTRUP00000000572 | ENSTRUP00000065422 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | Protoporphyrin/coproporphyrin ferrochelatase. | 0.667 |
| coq3 | coq2 | ENSTRUP00000000572 | ENSTRUP00000043156 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.809 |
| coq3 | hmbs | ENSTRUP00000000572 | ENSTRUP00000085986 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | Hydroxymethylbilane synthase a. | 0.676 |
| coq3 | itih2 | ENSTRUP00000000572 | ENSTRUP00000027282 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | Inter-alpha-trypsin inhibitor heavy chain 2. | 0.912 |
| coq3 | ppox | ENSTRUP00000000572 | ENSTRUP00000011985 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.687 |
| gmps | H2UMT2_TAKRU | ENSTRUP00000066154 | ENSTRUP00000079437 | Guanine monophosphate synthase. | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | 0.920 |
| gmps | NT5E | ENSTRUP00000066154 | ENSTRUP00000011279 | Guanine monophosphate synthase. | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | 0.920 |