Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
marchf4Membrane-associated ring finger (C3HC4) 4. (399 aa)    
Predicted Functional Partners:
ube2ql1
Ubiquitin-conjugating enzyme E2Q family-like 1.
      
 0.647
gpatch2
G-patch domain containing 2.
      
 0.640
ogfod1
2-oxoglutarate and iron-dependent oxygenase domain containing 1.
      
 0.592
kctd3
BTB domain-containing protein.
      
 0.583
spata17
Uncharacterized protein.
    
 
 0.552
rrp15
Ribosomal RNA processing 15 homolog.
      
 0.543
RRP15
Ribosomal RNA processing 15 homolog.
      
 0.543
ube2j2
Ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast).
    
 
 0.506
ENSTRUP00000070686
C1q and TNF related 12.
    
 
 0.506
cd6
Uncharacterized protein.
      
 0.459
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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