Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
erp44Endoplasmic reticulum protein 44. (354 aa)    
Predicted Functional Partners:
prdx4
Peroxiredoxin 4.
  
 0.897
ero1b
Endoplasmic reticulum oxidoreductase beta.
   
 0.880
ero1a
Endoplasmic reticulum oxidoreductase alpha.
   
 0.880
tgf-beta1
Transforming growth factor beta; Belongs to the TGF-beta family.
    
   0.868
dnajb11
DnaJ heat shock protein family (Hsp40) member B11.
   
 0.800
rpl13a
Ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family.
     
 0.702
SMARCE1
HMG box domain-containing protein.
      
 0.661
ppil2
Peptidylprolyl isomerase (cyclophilin)-like 2.
    
 0.648
LOC115248454
RING-box protein 1.
      
 0.630
LOC101079814
Ring-box 1, E3 ubiquitin protein ligase.
      
 0.630
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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