Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cln8CLN8 transmembrane ER and ERGIC protein. (288 aa)    
Predicted Functional Partners:
cln5
CLN5 intracellular trafficking protein.
      
 0.890
cln3
Battenin.
      
 0.878
ppt1
Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile).
      
 0.876
mfsd8
Major facilitator superfamily domain containing 8.
      
 0.873
tpp1
Tripeptidyl peptidase I.
    
 
 0.724
cln6
CLN6 transmembrane ER protein a.
      
 0.701
ENSTRUP00000058995
annotation not available
      
 0.701
lrguk
Leucine-rich repeats and guanylate kinase domain containing.
    
 
 0.664
arsg
Arylsulfatase G.
      
 0.640
atp13a2
Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
   
  
 0.633
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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