Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
sipa1l3Signal-induced proliferation-associated 1 like protein 3. (1761 aa)    
Predicted Functional Partners:
ap5b1
Adaptor related protein complex 5 subunit beta 1.
      
 0.606
LOC101074250
RAP1A, member of RAS oncogene family a.
    
 0.536
LOC101064935
Uncharacterized protein.
    
 0.536
LOC101070080
Uncharacterized protein.
    
 0.536
rap1a
Uncharacterized protein.
    
 0.536
ralgapb
Ral GTPase activating protein, beta subunit (non-catalytic).
   
 0.492
lzts2
Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family.
    
 0.476
ENSTRUP00000083198
Leucine zipper putative tumor suppressor 3.
    
 0.476
H2RNF6_TAKRU
Leucine zipper, putative tumor suppressor 1.
    
 
 0.471
rap2b
RAP2B, member of RAS oncogene family.
    
 0.467
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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