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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccdc174Coiled-coil domain containing 174. (543 aa)    
Predicted Functional Partners:
tatdn2
TatD DNase domain containing 2.
   
  
 0.766
dld
Dihydrolipoyl dehydrogenase.
   
    0.722
nrde2
NRDE-2, necessary for RNA interference, domain containing.
    
 
 0.711
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
   
  
 0.656
eif4a3
Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.
    
 
 0.598
dock4
Dedicator of cytokinesis 4b; Belongs to the DOCK family.
     
 0.583
crbn
Cereblon.
      
 0.562
DNM1L
Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
      
 0.545
anln
Anillin, actin binding protein.
   
 
 0.542
LOC105418333
Anillin domain-containing protein.
   
 
 0.542
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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