Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ccdc174Coiled-coil domain containing 174. (543 aa)    
Predicted Functional Partners:
eif4a3
Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.
    
 
 0.922
nrde2
NRDE-2, necessary for RNA interference, domain containing.
    
 
 0.888
tatdn2
TatD DNase domain containing 2.
   
  
 0.872
dld
Dihydrolipoyl dehydrogenase.
   
    0.733
nom1
Nucleolar protein with MIF4G domain 1.
      
 0.697
LOC101068307
G-patch domain-containing protein.
    
 
 0.683
crbn
Cereblon.
      
 0.672
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
   
    0.671
mtrex
Mtr4 exosome RNA helicase.
    
 
 0.660
LOC101078086
Uncharacterized protein.
   
  
 0.657
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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