Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101072929Transcription factor SOX. (371 aa)    
Predicted Functional Partners:
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.645
tcf7
Transcription factor 7.
    
 0.626
lef1
Lymphoid enhancer-binding factor 1.
    
 0.584
LOC101074260
POU domain protein.
    
 0.530
sox13
SRY-box transcription factor 13.
   
 0.518
LOC101071517
SRY-box transcription factor 6.
   
0.497
LOC101079931
Junction plakoglobin a.
    
 0.477
LOC101074632
HMG box domain-containing protein.
    
 0.477
LOC105419230
Uncharacterized protein.
    
 0.477
tcf7l1
Transcription factor 7 like 1b.
    
 0.477
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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