Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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LOC115247877Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (94 aa)    
Predicted Functional Partners:
LOC101077498
Guanine nucleotide binding protein (G protein), beta 5b.
   
 0.881
LOC101074575
Guanine nucleotide binding protein (G protein), beta 5a.
   
 0.881
LOC101080055
Purinergic receptor P2Y12.
    
  0.847
pik3r5
Phosphoinositide-3-kinase, regulatory subunit 5.
    
 0.845
calcr
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
    
  0.843
Sem1
SEM1 26S proteasome complex subunit.
   
    0.841
LOC101069591
PH_14 domain-containing protein.
    
 0.831
PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
    
 0.831
LOC101066106
G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
  0.827
LOC101065996
GNAS complex locus.
   
 0.823
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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