Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
fam189bSi:dkey-7f3.9. (723 aa)    
Predicted Functional Partners:
wwox
WW domain containing oxidoreductase.
    
 
 0.902
fam189a2
Family with sequence similarity 189 member A2.
    
 
 0.754
LOC101061475
E3 ubiquitin-protein ligase.
    
 0.699
LOC101070007
E3 ubiquitin-protein ligase.
    
 0.699
ankrd13d
Ankyrin repeat domain 13 family, member D.
    
   0.637
synrg
Synergin, gamma.
    
 0.597
ndfip2
Uncharacterized protein.
   
  
 0.594
hecw1
Si:ch211-188f17.1.
    
 0.587
LOC101077161
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2a.
    
 0.587
nedd4l
NEDD4 like E3 ubiquitin protein ligase.
    
 0.548
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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