Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
usp36Ubiquitin specific peptidase 36; Belongs to the peptidase C19 family. (1120 aa)    
Predicted Functional Partners:
suds3
SDS3 homolog, SIN3A corepressor complex component.
    
 0.781
fau
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
 0.643
usp28
Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family.
    
 0.641
rce1
Ras converting CAAX endopeptidase 1a.
     
 0.639
ENSTRUP00000074619
annotation not available
     
 0.639
LOC101079595
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
  0.611
ifih1
Interferon induced with helicase C domain 1.
     
 0.591
USP24
Ubiquitin specific peptidase 24.
     
0.591
cdc25b
Cell division cycle 25B.
    
 0.591
dhx33
DEAH (Asp-Glu-Ala-His) box polypeptide 33.
    
 
 0.572
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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