Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101071804Paraspeckle component 1. (515 aa)    
Predicted Functional Partners:
nudt21
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
   
 
 0.745
H2SWV4_TAKRU
RRM domain-containing protein.
   
 
 0.658
u2af2
U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.
   
 
 0.658
cdc5l
CDC5 cell division cycle 5-like (S. pombe).
   
 
 0.655
LOC101077614
TPR_REGION domain-containing protein.
   
 
 0.633
gtpbp6
GTP binding protein 6 (putative).
    
   0.597
hnrnpm
Heterogeneous nuclear ribonucleoprotein M.
   
 
 0.574
ewsr1
EWS RNA-binding protein 1b.
   
 
 0.556
dhx9
DRBM domain-containing protein.
   
 
 0.555
LOC101062985
RNA-binding protein FUS.
   
 
 0.536
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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