phrf1 protein (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

phrf1

PHD and ring finger domains 1. (1564 aa)

Predicted Functional Partners:

polr2g

0.625

dnmt1

0.573

eif4a3

0.528

deaf1

0.519

LOC101074452

0.481

gtf3c1

0.450

apip

0.445

LOC101073159

0.445

med25

0.440

sppl3

0.439

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101073159	phrf1	ENSTRUP00000055466	ENSTRUP00000028633	HIG1 hypoxia inducible domain family, member 2A.	PHD and ring finger domains 1.	0.445
LOC101074452	eif4a3	ENSTRUP00000078039	ENSTRUP00000029160	Mago homolog, exon junction complex subunit.	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	0.995
LOC101074452	phrf1	ENSTRUP00000078039	ENSTRUP00000028633	Mago homolog, exon junction complex subunit.	PHD and ring finger domains 1.	0.481
apip	phrf1	ENSTRUP00000041550	ENSTRUP00000028633	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.	PHD and ring finger domains 1.	0.445
apip	sppl3	ENSTRUP00000041550	ENSTRUP00000082857	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.	Signal peptide peptidase 3.	0.608
deaf1	phrf1	ENSTRUP00000078059	ENSTRUP00000028633	DEAF1 transcription factor.	PHD and ring finger domains 1.	0.519
dnmt1	phrf1	ENSTRUP00000020322	ENSTRUP00000028633	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	PHD and ring finger domains 1.	0.573
eif4a3	LOC101074452	ENSTRUP00000029160	ENSTRUP00000078039	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	Mago homolog, exon junction complex subunit.	0.995
eif4a3	phrf1	ENSTRUP00000029160	ENSTRUP00000028633	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	PHD and ring finger domains 1.	0.528
gtf3c1	phrf1	ENSTRUP00000074448	ENSTRUP00000028633	B-block_TFIIIC domain-containing protein.	PHD and ring finger domains 1.	0.450
med25	phrf1	ENSTRUP00000067210	ENSTRUP00000028633	Mediator complex subunit 25.	PHD and ring finger domains 1.	0.440
med25	polr2g	ENSTRUP00000067210	ENSTRUP00000049548	Mediator complex subunit 25.	Polymerase (RNA) II (DNA directed) polypeptide G-like.	0.640
phrf1	LOC101073159	ENSTRUP00000028633	ENSTRUP00000055466	PHD and ring finger domains 1.	HIG1 hypoxia inducible domain family, member 2A.	0.445
phrf1	LOC101074452	ENSTRUP00000028633	ENSTRUP00000078039	PHD and ring finger domains 1.	Mago homolog, exon junction complex subunit.	0.481
phrf1	apip	ENSTRUP00000028633	ENSTRUP00000041550	PHD and ring finger domains 1.	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.	0.445
phrf1	deaf1	ENSTRUP00000028633	ENSTRUP00000078059	PHD and ring finger domains 1.	DEAF1 transcription factor.	0.519
phrf1	dnmt1	ENSTRUP00000028633	ENSTRUP00000020322	PHD and ring finger domains 1.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.573
phrf1	eif4a3	ENSTRUP00000028633	ENSTRUP00000029160	PHD and ring finger domains 1.	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	0.528
phrf1	gtf3c1	ENSTRUP00000028633	ENSTRUP00000074448	PHD and ring finger domains 1.	B-block_TFIIIC domain-containing protein.	0.450
phrf1	med25	ENSTRUP00000028633	ENSTRUP00000067210	PHD and ring finger domains 1.	Mediator complex subunit 25.	0.440