Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smpdl3aAcid sphingomyelinase-like phosphodiesterase. (440 aa)    
Predicted Functional Partners:
brinp1
Bone morphogenetic protein/retinoic acid inducible neural-specific 1.
      
 0.858
LOC101076350
BTB (POZ) domain containing 10a.
      
 0.743
znf330
Zinc finger protein 330.
      
 0.721
rbm48
RNA binding motif protein 48.
      
 0.717
ttc9c
Tetratricopeptide repeat domain 9C.
      
 0.632
vwde
Uncharacterized protein.
      
 0.631
LOC101062470
Zinc finger protein 574.
      
 0.605
LOC101067169
Sulfide quinone oxidoreductase.
      
 0.597
ENSTRUP00000054247
Sulfide quinone oxidoreductase.
      
 0.597
togaram1
Uncharacterized protein.
      
 0.589
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (16%) [HD]