elp5 protein (Takifugu rubripes) - STRING interaction network

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Score

elp5

Elongator acetyltransferase complex subunit 5. (289 aa)

Predicted Functional Partners:

elp4

0.996

elp1

0.988

elp3

0.976

elp6

0.955

elp2

0.807

kti12

0.768

ENSTRUP00000085478

0.768

ctu1

0.739

mocs3

0.685

pipox

0.662

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSTRUP00000085478	ctu1	ENSTRUP00000085478	ENSTRUP00000041385	Neuromedin Bb.	Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.	0.498
ENSTRUP00000085478	elp1	ENSTRUP00000085478	ENSTRUP00000004322	Neuromedin Bb.	Uncharacterized protein.	0.768
ENSTRUP00000085478	elp3	ENSTRUP00000085478	ENSTRUP00000007288	Neuromedin Bb.	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	0.834
ENSTRUP00000085478	elp4	ENSTRUP00000085478	ENSTRUP00000017660	Neuromedin Bb.	Elongator acetyltransferase complex subunit 4.	0.612
ENSTRUP00000085478	elp5	ENSTRUP00000085478	ENSTRUP00000028796	Neuromedin Bb.	Elongator acetyltransferase complex subunit 5.	0.768
ENSTRUP00000085478	mocs3	ENSTRUP00000085478	ENSTRUP00000021774	Neuromedin Bb.	Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]	0.502
ctu1	ENSTRUP00000085478	ENSTRUP00000041385	ENSTRUP00000085478	Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.	Neuromedin Bb.	0.498
ctu1	elp1	ENSTRUP00000041385	ENSTRUP00000004322	Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.	Uncharacterized protein.	0.732
ctu1	elp2	ENSTRUP00000041385	ENSTRUP00000027989	Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.	Elongator acetyltransferase complex subunit 2.	0.526
ctu1	elp3	ENSTRUP00000041385	ENSTRUP00000007288	Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	0.809
ctu1	elp4	ENSTRUP00000041385	ENSTRUP00000017660	Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.	Elongator acetyltransferase complex subunit 4.	0.695
ctu1	elp5	ENSTRUP00000041385	ENSTRUP00000028796	Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.	Elongator acetyltransferase complex subunit 5.	0.739
ctu1	kti12	ENSTRUP00000041385	ENSTRUP00000048340	Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.	KTI12 chromatin associated homolog.	0.498
ctu1	mocs3	ENSTRUP00000041385	ENSTRUP00000021774	Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.	Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]	0.809
elp1	ENSTRUP00000085478	ENSTRUP00000004322	ENSTRUP00000085478	Uncharacterized protein.	Neuromedin Bb.	0.768
elp1	ctu1	ENSTRUP00000004322	ENSTRUP00000041385	Uncharacterized protein.	Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.	0.732
elp1	elp2	ENSTRUP00000004322	ENSTRUP00000027989	Uncharacterized protein.	Elongator acetyltransferase complex subunit 2.	0.976
elp1	elp3	ENSTRUP00000004322	ENSTRUP00000007288	Uncharacterized protein.	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	0.994
elp1	elp4	ENSTRUP00000004322	ENSTRUP00000017660	Uncharacterized protein.	Elongator acetyltransferase complex subunit 4.	0.993
elp1	elp5	ENSTRUP00000004322	ENSTRUP00000028796	Uncharacterized protein.	Elongator acetyltransferase complex subunit 5.	0.988