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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
irf7Interferon regulatory factor 7. (469 aa)    
Predicted Functional Partners:
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.996
LOC101071639
Interferon regulatory factor 3.
   
0.990
LOC101061773
Interleukin-1 receptor-associated kinase 1.
   
 0.966
ikbke
Protein kinase domain-containing protein.
   
 0.953
LOC101068225
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.945
ticam
Toll-like receptor adaptor molecule.
   
 0.943
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.939
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.938
LOC115251511
Interferon a3-like.
     
 0.905
traf3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.875
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.