STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101072117Histone H2A; Belongs to the histone H2A family. (138 aa)    
Predicted Functional Partners:
mysm1
Histone H2A deubiquitinase MYSM1.
    
 0.963
LOC101065748
Lysine (K)-specific demethylase 6B, a.
    
 0.728
LOC101078029
Uncharacterized protein.
    
 0.715
kdm6a
Lysine (K)-specific demethylase 6A, like.
    
 0.715
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.712
H2AZ1
Histone H2A; Belongs to the histone H2A family.
  
0.698
LOC101080230
Histone H2A; Belongs to the histone H2A family.
  
0.697
LOC101068156
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.696
LOC101068156-2
Histone H4.
 
 
 0.696
LOC101068156-3
Histone H4.
 
 
 0.696
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.