LOC101074469 protein (Takifugu rubripes) - STRING interaction network

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LOC101074469

5'-nucleotidase, cytosolic IAb. (380 aa)

Predicted Functional Partners:

ak3

0.931

tyms

0.921

NT5E

0.919

entpd3

0.919

H2UMT2_TAKRU

0.919

ITPA

0.918

adsl

0.915

atic

0.915

LOC105416930

0.912

LOC101078071

0.910

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H2UMT2_TAKRU	ITPA	ENSTRUP00000079437	ENSTRUP00000068546	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	0.911
H2UMT2_TAKRU	LOC101074469	ENSTRUP00000079437	ENSTRUP00000029031	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	5'-nucleotidase, cytosolic IAb.	0.919
H2UMT2_TAKRU	LOC101078071	ENSTRUP00000079437	ENSTRUP00000002765	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	5'-nucleotidase, cytosolic IIa.	0.911
H2UMT2_TAKRU	LOC105416930	ENSTRUP00000079437	ENSTRUP00000055504	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	Uncharacterized protein.	0.900
H2UMT2_TAKRU	NT5E	ENSTRUP00000079437	ENSTRUP00000011279	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	0.903
H2UMT2_TAKRU	adsl	ENSTRUP00000079437	ENSTRUP00000048596	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	Adenylosuccinate lyase.	0.930
H2UMT2_TAKRU	ak3	ENSTRUP00000079437	ENSTRUP00000026774	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	0.903
H2UMT2_TAKRU	atic	ENSTRUP00000079437	ENSTRUP00000063031	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	0.923
H2UMT2_TAKRU	entpd3	ENSTRUP00000079437	ENSTRUP00000023436	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family.	0.945
H2UMT2_TAKRU	tyms	ENSTRUP00000079437	ENSTRUP00000049317	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	Thymidylate synthetase.	0.916
ITPA	H2UMT2_TAKRU	ENSTRUP00000068546	ENSTRUP00000079437	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	0.911
ITPA	LOC101074469	ENSTRUP00000068546	ENSTRUP00000029031	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	5'-nucleotidase, cytosolic IAb.	0.918
ITPA	LOC101078071	ENSTRUP00000068546	ENSTRUP00000002765	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	5'-nucleotidase, cytosolic IIa.	0.907
ITPA	LOC105416930	ENSTRUP00000068546	ENSTRUP00000055504	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	Uncharacterized protein.	0.900
ITPA	NT5E	ENSTRUP00000068546	ENSTRUP00000011279	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	0.911
ITPA	adsl	ENSTRUP00000068546	ENSTRUP00000048596	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	Adenylosuccinate lyase.	0.486
ITPA	atic	ENSTRUP00000068546	ENSTRUP00000063031	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	0.951
ITPA	entpd3	ENSTRUP00000068546	ENSTRUP00000023436	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family.	0.909
ITPA	tyms	ENSTRUP00000068546	ENSTRUP00000049317	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	Thymidylate synthetase.	0.875
LOC101074469	H2UMT2_TAKRU	ENSTRUP00000029031	ENSTRUP00000079437	5'-nucleotidase, cytosolic IAb.	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	0.919