Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101061475E3 ubiquitin-protein ligase. (879 aa)    
Predicted Functional Partners:
LOC101062685
Notch receptor 1a.
    
 0.965
LOC101067059
Notch receptor 1b.
    
 0.965
LOC101078599
Notch receptor 3.
    
  0.926
LOC101080224
Notch receptor 2.
    
  0.926
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.915
cflar
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 
 0.900
rps27a
Ribosomal protein S27a.
    
  0.892
spart
Spartin b.
    
 
 0.885
txnip
Thioredoxin interacting protein.
    
 
 0.875
rnf11
Ring finger protein 11b.
    
 0.846
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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