Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ksr1Kinase suppressor of ras 1a. (987 aa)    
Predicted Functional Partners:
raf1
Uncharacterized protein.
    
0.977
LOC101079403
Kinase suppressor of ras 1b.
  
  
 
0.901
map2k2
Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.
   
 0.837
map2k1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
   
 0.837
brap
BRCA1 associated protein.
    
 0.833
map2k5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
   
 0.832
araf
Uncharacterized protein.
    
 0.786
braf
Uncharacterized protein.
    
 0.786
cnksr1
Connector enhancer of kinase suppressor of Ras 1.
    
 0.755
pebp1
Phosphatidylethanolamine binding protein 1.
    
 0.685
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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