Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GHITMGrowth hormone inducible transmembrane protein; Belongs to the BI1 family. (348 aa)    
Predicted Functional Partners:
ndufa11
NADH:ubiquinone oxidoreductase subunit A11.
   
   0.927
tmbim6
Testis enhanced gene transcript (BAX inhibitor 1); Belongs to the BI1 family.
   
  
 0.745
clrn3
Clarin 3.
      
 0.727
mre11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
      
 0.727
vamp7
Synaptobrevin-like 1; Belongs to the synaptobrevin family.
   
  
 0.707
gdap1
Ganglioside induced differentiation associated protein 1.
      
 0.695
vti1a
Vesicle transport through interaction with t-SNAREs 1A.
   
  
 0.689
LOC101062208
Voltage-dependent calcium channel beta subunit-associated regulatory protein-like.
      
 0.608
cbarp
Voltage-dependent calcium channel beta subunit-associated regulatory protein.
      
 0.608
LOC101069505
40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family.
      
 0.603
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (30%) [HD]