STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101073766Tumor necrosis factor, alpha-induced protein 8-like 1. (186 aa)    
Predicted Functional Partners:
fbxw5
F-box and WD repeat domain containing 5.
    
 
 0.643
ppp1r14c
Protein phosphatase 1, regulatory (inhibitor) subunit 14C.
      
 0.588
MED4
Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
   0.572
LOC101077980
RIC8 guanine nucleotide exchange factor A.
      
 0.567
Ccndbp1
Cyclin-D1-binding protein 1 isoform X1.
      
 0.514
tinagl1
Tubulointerstitial nephritis antigen like 1; Belongs to the peptidase C1 family.
      
 0.488
tnfaip3
Tumor necrosis factor, alpha-induced protein 3.
    
 
 0.468
LOC101069848
Retinoblastoma-associated protein.
      
 0.458
LOC115246431
Retinoblastoma 1.
      
 0.452
LOC101064950
DnaJ (Hsp40) homolog, subfamily C, member 1.
      
 0.445
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (18%) [HD]