STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
epg5Ectopic P-granules autophagy protein 5 homolog (C. elegans). (2542 aa)    
Predicted Functional Partners:
GABARAPL2
GABA(A) receptor-associated protein like 2.
    
 0.941
LOC101065324
Microtubule-associated protein 1 light chain 3 beta.
    
 0.940
LOC101062775
Microtubule-associated protein 1 light chain 3 gamma, like.
    
 0.921
LOC101076880
Zgc:92606.
    
 0.921
map1lc3c
Microtubule-associated protein 1 light chain 3 gamma.
    
 0.921
LOC101076529
RAB7a, member RAS oncogene family.
     
 0.904
LOC101061812
RAB7A, member RAS oncogene family.
     
 0.904
snap29
Synaptosome associated protein 29.
      
 0.706
atg5
Autophagy protein 5; Involved in autophagic vesicle formation.
      
 0.704
atg7
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
      
 0.701
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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