erbb3 protein (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

erbb3

Protein kinase domain-containing protein. (1423 aa)

Predicted Functional Partners:

LOC101075752

0.984

grb2

0.974

LOC101061204

0.974

SHC3

0.969

shc1

0.969

nrg2

0.969

shc4

0.969

shc2

0.962

LOC101063692

0.943

LOC101061527

0.943

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101061204	LOC101061527	ENSTRUP00000049272	ENSTRUP00000030225	Uncharacterized protein.	Uncharacterized protein.	0.674
LOC101061204	LOC101063692	ENSTRUP00000049272	ENSTRUP00000026411	Uncharacterized protein.	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	0.733
LOC101061204	LOC101075752	ENSTRUP00000049272	ENSTRUP00000070829	Uncharacterized protein.	Neuregulin 2b.	0.457
LOC101061204	SHC3	ENSTRUP00000049272	ENSTRUP00000026157	Uncharacterized protein.	SHC adaptor protein 3.	0.982
LOC101061204	erbb3	ENSTRUP00000049272	ENSTRUP00000029436	Uncharacterized protein.	Protein kinase domain-containing protein.	0.974
LOC101061204	grb2	ENSTRUP00000049272	ENSTRUP00000020659	Uncharacterized protein.	Growth factor receptor-bound protein 2b.	0.903
LOC101061204	nrg2	ENSTRUP00000049272	ENSTRUP00000069343	Uncharacterized protein.	Neuregulin 2a.	0.457
LOC101061204	shc1	ENSTRUP00000049272	ENSTRUP00000055854	Uncharacterized protein.	SHC (Src homology 2 domain containing) transforming protein 1.	0.982
LOC101061204	shc2	ENSTRUP00000049272	ENSTRUP00000023381	Uncharacterized protein.	SHC (Src homology 2 domain containing) transforming protein 2.	0.962
LOC101061204	shc4	ENSTRUP00000049272	ENSTRUP00000086042	Uncharacterized protein.	SHC-transforming protein 4 isoform X2.	0.982
LOC101061527	LOC101061204	ENSTRUP00000030225	ENSTRUP00000049272	Uncharacterized protein.	Uncharacterized protein.	0.674
LOC101061527	LOC101063692	ENSTRUP00000030225	ENSTRUP00000026411	Uncharacterized protein.	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	0.903
LOC101061527	SHC3	ENSTRUP00000030225	ENSTRUP00000026157	Uncharacterized protein.	SHC adaptor protein 3.	0.512
LOC101061527	erbb3	ENSTRUP00000030225	ENSTRUP00000029436	Uncharacterized protein.	Protein kinase domain-containing protein.	0.943
LOC101061527	grb2	ENSTRUP00000030225	ENSTRUP00000020659	Uncharacterized protein.	Growth factor receptor-bound protein 2b.	0.674
LOC101061527	shc1	ENSTRUP00000030225	ENSTRUP00000055854	Uncharacterized protein.	SHC (Src homology 2 domain containing) transforming protein 1.	0.512
LOC101061527	shc2	ENSTRUP00000030225	ENSTRUP00000023381	Uncharacterized protein.	SHC (Src homology 2 domain containing) transforming protein 2.	0.465
LOC101061527	shc4	ENSTRUP00000030225	ENSTRUP00000086042	Uncharacterized protein.	SHC-transforming protein 4 isoform X2.	0.512
LOC101063692	LOC101061204	ENSTRUP00000026411	ENSTRUP00000049272	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Uncharacterized protein.	0.733
LOC101063692	LOC101061527	ENSTRUP00000026411	ENSTRUP00000030225	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Uncharacterized protein.	0.903