Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
r3hdm1R3H domain containing 1. (376 aa)    
Predicted Functional Partners:
polr3b
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.509
elp5
Elongator acetyltransferase complex subunit 5.
      
 0.495
copz1
Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
      
 0.491
LOC101064659
Uncharacterized protein.
    
 
 0.442
UPF1
Putative regulator of nonsense transcripts 1; RNA-dependent helicase and ATPase required for nonsense- mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited to mRNAs upon translation termination and undergoes a cycle of phosphorylation and dephosphorylation; its phosphorylation appears to be a key step in NMD. The formation of an rent1-rent2-rent3 surveillance complex is believed to activate NMD (By similarity).
    
 
 0.442
LOC101078026
RNA polymerase I and III subunit D.
    
 
 0.439
babam2
BRISC and BRCA1 A complex member 2.
    
 
 0.434
nif3l1
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae).
      
 0.426
pmpcb
Peptidase (mitochondrial processing) beta; Belongs to the peptidase M16 family.
   
   0.421
LOC101077128
Ubiquinol-cytochrome c reductase core protein 1.
   
   0.421
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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