STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prpf39PRP39 pre-mRNA processing factor 39 homolog (yeast). (759 aa)    
Predicted Functional Partners:
snrpc
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]
   
 0.896
LOC101076679
tRNA selenocysteine 1 associated protein 1b.
   
 
 0.883
snrnp70
Small nuclear ribonucleoprotein 70 (U1).
   
 0.875
snrpf
Small nuclear ribonucleoprotein polypeptide F.
    
 0.872
sf3b1
Splicing factor 3b, subunit 1.
   
 
 0.852
LOC101065025
Zgc:158803.
   
 0.826
luc7l
LUC7-like (S. cerevisiae).
   
 0.826
rbm25
RNA binding motif protein 25b.
   
 
 0.811
pnisr
PNN-interacting serine/arginine-rich protein.
   
  
 0.806
LOC101067317
Uncharacterized protein.
   
 0.803
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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