Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gp91phoxGp91phox protein. (580 aa)    
Predicted Functional Partners:
p22phox
Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
   
 0.993
ncf1
Uncharacterized protein.
   
 0.985
ncf4
Uncharacterized protein.
   
 0.948
LOC101071995
Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2; Belongs to the protein kinase superfamily.
     
  0.900
NAMPT
Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.
     
  0.900
LOC101068297
Calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2.
     
  0.900
H2UVZ3_TAKRU
Protein kinase domain-containing protein.
     
  0.900
ENSTRUP00000067358
NADPH oxidase activator 1.
  
 0.876
LOC101073453
Dual oxidase 2.
   
 0.854
NOX4
FAD-binding FR-type domain-containing protein.
  
 
0.848
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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