| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FANCA | Fancm | ENSTRUP00000080350 | ENSTRUP00000024507 | Fanconi anemia group A protein. | ERCC4 domain-containing protein. | 0.999 |
| FANCA | blm | ENSTRUP00000080350 | ENSTRUP00000078695 | Fanconi anemia group A protein. | BLM RecQ like helicase. | 0.975 |
| FANCA | mus81 | ENSTRUP00000080350 | ENSTRUP00000059894 | Fanconi anemia group A protein. | MUS81 structure-specific endonuclease subunit. | 0.867 |
| FANCA | rad51 | ENSTRUP00000080350 | ENSTRUP00000052909 | Fanconi anemia group A protein. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.729 |
| FANCA | rmi1 | ENSTRUP00000080350 | ENSTRUP00000026696 | Fanconi anemia group A protein. | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). | 0.962 |
| FANCA | rmi2 | ENSTRUP00000080350 | ENSTRUP00000032434 | Fanconi anemia group A protein. | RecQ mediated genome instability 2. | 0.963 |
| FANCA | top3a | ENSTRUP00000080350 | ENSTRUP00000081442 | Fanconi anemia group A protein. | DNA topoisomerase 3-alpha. | 0.921 |
| FANCA | top3a-2 | ENSTRUP00000080350 | ENSTRUP00000063973 | Fanconi anemia group A protein. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.921 |
| FANCA | xrcc3 | ENSTRUP00000080350 | ENSTRUP00000041433 | Fanconi anemia group A protein. | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. | 0.525 |
| Fancm | FANCA | ENSTRUP00000024507 | ENSTRUP00000080350 | ERCC4 domain-containing protein. | Fanconi anemia group A protein. | 0.999 |
| Fancm | blm | ENSTRUP00000024507 | ENSTRUP00000078695 | ERCC4 domain-containing protein. | BLM RecQ like helicase. | 0.998 |
| Fancm | mus81 | ENSTRUP00000024507 | ENSTRUP00000059894 | ERCC4 domain-containing protein. | MUS81 structure-specific endonuclease subunit. | 0.991 |
| Fancm | rad51 | ENSTRUP00000024507 | ENSTRUP00000052909 | ERCC4 domain-containing protein. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.971 |
| Fancm | rmi1 | ENSTRUP00000024507 | ENSTRUP00000026696 | ERCC4 domain-containing protein. | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). | 0.987 |
| Fancm | rmi2 | ENSTRUP00000024507 | ENSTRUP00000032434 | ERCC4 domain-containing protein. | RecQ mediated genome instability 2. | 0.998 |
| Fancm | top3a | ENSTRUP00000024507 | ENSTRUP00000081442 | ERCC4 domain-containing protein. | DNA topoisomerase 3-alpha. | 0.995 |
| Fancm | top3a-2 | ENSTRUP00000024507 | ENSTRUP00000063973 | ERCC4 domain-containing protein. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.995 |
| Fancm | top3b | ENSTRUP00000024507 | ENSTRUP00000067299 | ERCC4 domain-containing protein. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.988 |
| Fancm | xrcc3 | ENSTRUP00000024507 | ENSTRUP00000041433 | ERCC4 domain-containing protein. | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. | 0.926 |
| blm | FANCA | ENSTRUP00000078695 | ENSTRUP00000080350 | BLM RecQ like helicase. | Fanconi anemia group A protein. | 0.975 |
