STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rmi2RecQ mediated genome instability 2. (138 aa)    
Predicted Functional Partners:
Fancm
ERCC4 domain-containing protein.
    
 0.999
rmi1
RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae).
    
 0.995
blm
BLM RecQ like helicase.
   
 0.988
top3a-2
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.979
top3a
DNA topoisomerase 3-alpha.
    
 0.979
FANCA
Fanconi anemia group A protein.
   
 
 0.938
tdrd3
Tudor domain containing 3.
    
 0.937
slf1
SMC5-SMC6 complex localization factor protein 1.
     
 0.930
mus81
MUS81 structure-specific endonuclease subunit.
    
 0.893
ercc4
Excision repair cross-complementation group 4.
    
 0.883
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.