rmi2 protein (Takifugu rubripes) - STRING interaction network

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[Homology]

Score

rmi2

RecQ mediated genome instability 2. (138 aa)

Predicted Functional Partners:

rmi1

0.999

blm

0.999

Fancm

0.998

top3a-2

0.996

top3a

0.996

FANCA

0.963

top3b

0.956

mus81

0.934

xrcc3

0.903

rad51

0.890

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FANCA	Fancm	ENSTRUP00000080350	ENSTRUP00000024507	Fanconi anemia group A protein.	ERCC4 domain-containing protein.	0.999
FANCA	blm	ENSTRUP00000080350	ENSTRUP00000078695	Fanconi anemia group A protein.	BLM RecQ like helicase.	0.975
FANCA	mus81	ENSTRUP00000080350	ENSTRUP00000059894	Fanconi anemia group A protein.	MUS81 structure-specific endonuclease subunit.	0.867
FANCA	rad51	ENSTRUP00000080350	ENSTRUP00000052909	Fanconi anemia group A protein.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.729
FANCA	rmi1	ENSTRUP00000080350	ENSTRUP00000026696	Fanconi anemia group A protein.	RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae).	0.962
FANCA	rmi2	ENSTRUP00000080350	ENSTRUP00000032434	Fanconi anemia group A protein.	RecQ mediated genome instability 2.	0.963
FANCA	top3a	ENSTRUP00000080350	ENSTRUP00000081442	Fanconi anemia group A protein.	DNA topoisomerase 3-alpha.	0.921
FANCA	top3a-2	ENSTRUP00000080350	ENSTRUP00000063973	Fanconi anemia group A protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.921
FANCA	xrcc3	ENSTRUP00000080350	ENSTRUP00000041433	Fanconi anemia group A protein.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.525
Fancm	FANCA	ENSTRUP00000024507	ENSTRUP00000080350	ERCC4 domain-containing protein.	Fanconi anemia group A protein.	0.999
Fancm	blm	ENSTRUP00000024507	ENSTRUP00000078695	ERCC4 domain-containing protein.	BLM RecQ like helicase.	0.998
Fancm	mus81	ENSTRUP00000024507	ENSTRUP00000059894	ERCC4 domain-containing protein.	MUS81 structure-specific endonuclease subunit.	0.991
Fancm	rad51	ENSTRUP00000024507	ENSTRUP00000052909	ERCC4 domain-containing protein.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.971
Fancm	rmi1	ENSTRUP00000024507	ENSTRUP00000026696	ERCC4 domain-containing protein.	RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae).	0.987
Fancm	rmi2	ENSTRUP00000024507	ENSTRUP00000032434	ERCC4 domain-containing protein.	RecQ mediated genome instability 2.	0.998
Fancm	top3a	ENSTRUP00000024507	ENSTRUP00000081442	ERCC4 domain-containing protein.	DNA topoisomerase 3-alpha.	0.995
Fancm	top3a-2	ENSTRUP00000024507	ENSTRUP00000063973	ERCC4 domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.995
Fancm	top3b	ENSTRUP00000024507	ENSTRUP00000067299	ERCC4 domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.988
Fancm	xrcc3	ENSTRUP00000024507	ENSTRUP00000041433	ERCC4 domain-containing protein.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.926
blm	FANCA	ENSTRUP00000078695	ENSTRUP00000080350	BLM RecQ like helicase.	Fanconi anemia group A protein.	0.975