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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lepLeptin; May function as part of a signaling pathway that acts to regulate the size of the body fat depot. (152 aa)    
Predicted Functional Partners:
lepr
Uncharacterized protein.
    
 0.901
LOC101064982
Proopiomelanocortin.
      
 0.792
LOC101071076
Peptide YYa.
      
 0.692
LOC101077703
Cholecystokinin a.
      
 0.660
LOC101076657
Neuropeptide Y.
      
 0.655
agrp1
Agouti domain-containing protein.
      
 0.652
LOC101063439
Gastrin domain-containing protein.
      
 0.638
crh
Corticotropin releasing hormone b.
      
 0.631
socs3
Suppressor of cytokine signaling 3a.
     
 0.623
mc2r
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
  
 0.601
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.