STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hddc2HD domain containing 2. (203 aa)    
Predicted Functional Partners:
adat3
Adenosine deaminase tRNA specific 3.
   
 
  0.646
smug1
Single-strand-selective monofunctional uracil-DNA glycosylase 1.
   
 
  0.646
adat2
CMP/dCMP-type deaminase domain-containing protein.
   
 
  0.646
mettl5
Methyltransferase like 5.
   
    0.644
LOC101070083
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
  0.636
ENSTRUP00000021618
Purine nucleoside phosphorylase 5a.
  
 
  0.636
LOC101072434
PNP_UDP_1 domain-containing protein.
  
 
  0.636
mtap
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 
  0.636
LOC101062429
Nudix (nucleoside diphosphate linked moiety X)-type motif 12.
    
  0.617
ENSTRUP00000052943
Uncharacterized protein.
    
  0.607
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (20%) [HD]